Creation Rebirth can be turned off, but there is no record that confirms that Hashirama’s regenerative abilities could be stopped. It is known as Hashirama was not the smartest ninja, so it is very likely that he could not figure out that his regenerative ability came at the cost of his own life. Despite the epicness of the fight, Madara managed to obliterate his opponents with ease, seemingly killing all of them, although – as it turned out – Tsunade survived. These are the two situations when Tsunade seemingly died, but as we can see, she survived both of them.

Well there is the possibility that while Naruto was fighting pain Danzo killed her but the possibility is very small. The other possibility is that she will die because she released that chakra diamond. With the help of their abilities, these ninjas have made a name for themselves and laid down a marker in the history books. In its rich past, the village has been the home to many legendary ninjas. However, there is one name that stands above the rest— Hashirama Senju, who was the First Hokage of the Hidden Leaf. Jiraiya and Orochimaru followed in the footsteps of the previous shinobis and used their techniques to become powerful.

Orochimaru and Kabuto state that they’ll force her to heal his arms, causing her to attack them. They draw her away from the city and Kabuto, a medic-nin, tries neutralising her, but she heals all the debilitating damage he does. Unable to stop her through conventional means, Kabuto slits his own wrists and coats her with his blood, paralysing her due to her phobia.

This would come to backfire spectacularly, as Akatsuki leader Nagato ultimately kills Jiraiya. Jiraiya does manage to send a message to Naruto that explains how Nagato could be defeated, however, before he dies. Jiraiya’s death is one of those fictional loses that fans are still dealing with. Jiraiya does rumchata go bad was Naruto’s mentor who dies trying to stop Pain from attacking Naruto and destroying the Hidden Leaf Village. … And as it turns out, he is indeed a character who shares DNA with the legendary Sannin. Hanare is a name that is tossed around a lot when fans begin to talk about Kakashi’s love life.

Tsunade is a compulsive gambler with terrible luck, albeit with a rare winning streak that she perceives as a bad omen. The pinnacle of her abilities is the Creation Rebirth Jutsu and the technique derived from it, the Strength of a Hundred Technique, which she taught to her disciple Sakura. In this way, both Tsunade and Sakura use mitotic regeneration to make them almost invincible in battle. She does get incapacitated due to the pain invasion along with most of the rest of the village which is what leads to Danzo becoming the next hokage candidate. But she never dies and she also survives madara’s numerous susanoo attacks.